SCHEMBL4845217

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21101485	0.77	ALDH1A1 (0.58)	CYP1A2CYP2C19HTTMEN1KMT2A
	SCHEMBL4848136	0.75	TRPV1 (0.61)	MEN1KMT2ATRPV1KDR
	SCHEMBL23087526	0.74	KDR (0.60)	CYP1A2HTTMEN1KMT2AHDAC6
	SCHEMBL4198986	0.71	EGFR (0.46)	MEN1KMT2ANPC1KDRRAB9A
	SCHEMBL4147660	0.71	HSD17B10 (0.48)	HTTMEN1KMT2AALDH1A1KDM4E
	SCHEMBL28242830	0.71	NPC1 (0.67)	CYP1A2CYP2C19HTTMEN1KMT2A
	SCHEMBL24703329	0.71	TRPV1 (0.67)	CYP1A2CYP2C19HTTMEN1KMT2A
	SCHEMBL440439	0.70	HTT (1.00)	CYP1A2CYP2C19HTTMEN1KMT2A
	SCHEMBL29361503	0.70	HTT (1.00)	CYP1A2CYP2C19HTTMEN1KMT2A
	SCHEMBL21282168	0.70	PIK3CA (0.48)	MEN1KMT2AALDH1A1TRPV1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.