Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851907 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9AKDM4EMAPK1 | |
| SCHEMBL4848079 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9AKDM4EMAPK1 | |
| SCHEMBL23183064 | 0.78 | KMT2A (0.57) | HDAC1ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL25491992 | 0.71 | TACR1 (0.59) | ALDH1A1MAPK1HPGDKMT2AMEN1 | |
| SCHEMBL25491998 | 0.71 | TACR1 (0.59) | ALDH1A1MAPK1HPGDKMT2AMEN1 | |
| SCHEMBL15635931 | 0.70 | CTSA (0.63) | — | |
| SCHEMBL15635930 | 0.70 | CTSA (0.63) | — | |
| SCHEMBL3791932 | 0.70 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2RAB9AKDM4EMAPK1 | |
| SCHEMBL7325387 | 0.70 | NPC1 (0.58) | ALDH1A1SMN1; SMN2RAB9AKDM4ENPC1 | |
| SCHEMBL7130097 | 0.70 | CASR (0.43) | RAB9AKDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323456-B2 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323456-B2 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323456-B2 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20040254370-A1 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1445256-A1 | CARBOXYLIC ACID DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254370-A1 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | SREBF1, GPR119, PPARG | HDAC1 141/4885ALDH1A1 355/4885SMN1; SMN2 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.