Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848079 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL4845407 | 0.86 | HDAC1 (0.49) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL4680782 | 0.78 | LMNA (0.52) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL6183765 | 0.75 | CTSL (0.59) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7325011 | 0.74 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL7326778 | 0.74 | RAB9A (0.71) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL6183960 | 0.74 | CTSL (0.60) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7325387 | 0.73 | NPC1 (0.58) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL30175325 | 0.73 | UBE2T (0.56) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL3895677 | 0.73 | RAB9A (0.72) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323456-B2 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323456-B2 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323456-B2 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20040254370-A1 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1445256-A1 | CARBOXYLIC ACID DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254370-A1 | Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient | SREBF1, GPR119, PPARG | ALDH1A1 355/4885SMN1; SMN2 4577/4885HPGD 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.