SCHEMBL484570

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12884286	0.91	GRM5 (0.65)	GRM5KCNH2TTRMAPTMEN1
	SCHEMBL5778843	0.85	GRM5 (0.62)	GRM5KCNH2TTRMEN1KMT2A
	SCHEMBL15422868	0.83	TTR (0.68)	GRM5KCNH2TTRMAPTMEN1
	SCHEMBL12884290	0.82	TTR (0.62)	GRM5KCNH2TTRMAPTALDH1A1
	SCHEMBL2808633	0.82	TTR (0.55)	GRM5KCNH2TTRMEN1KMT2A
	SCHEMBL21858065	0.79	GRM5 (0.56)	GRM5KCNH2TTRMEN1KMT2A
	SCHEMBL15877543	0.76	GRM5 (0.56)	GRM5KCNH2TTRNCF1NOS2
	SCHEMBL30824514	0.76	GRM5 (0.59)	GRM5KCNH2TTRMAPTMEN1
	SCHEMBL18546549	0.75	TTR (0.51)	GRM5KCNH2TTRMAPTMEN1
	SCHEMBL1109765	0.74	MAPT (0.48)	GRM5KCNH2TTRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.