Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.55 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889573 | 0.84 | PDE7A (0.54) | PDE7APDE7BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3506549 | 0.80 | PDE7A (0.56) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL30338244 | 0.79 | PDE7A (0.65) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL1713219 | 0.79 | PDE7A (0.65) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL2881438 | 0.76 | TDP1 (0.39) | PDE7AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3297230 | 0.76 | PDE7A (0.38) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL1451915 | 0.75 | MAOA (0.38) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL9709555 | 0.73 | PDE7A (0.58) | PDE7APDE7BMAPTMEN1KMT2A | |
| SCHEMBL19048971 | 0.73 | PDE7A (0.71) | PDE7APDE7BMAPTMEN1KMT2A | |
| Diphenylsulfane SCHEMBL27370215 | 0.73 | PDE7A (0.56) | PDE7APDE7BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323458-B1 | Dihydrobenzodiazepins and their use for treating dyslipidemia | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-29 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |