Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849521 | 0.90 | ALDH1A1 (0.43) | POLBALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL4843039 | 0.86 | POLB (0.48) | POLBALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL14193612 | 0.81 | CYP3A4 (0.44) | POLBALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL21363675 | 0.81 | CYP3A4 (0.44) | POLBALDH1A1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL4843143 | 0.81 | CYP3A4 (0.54) | ALDH1A1SMN1; SMN2CYP3A4CYP1A2TSHR | |
| SCHEMBL30262896 | 0.78 | POLB (0.43) | POLBALDH1A1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL14552371 | 0.77 | POLB (0.61) | POLBALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL21363678 | 0.73 | CDK4 (0.45) | POLBALDH1A1L3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL14193623 | 0.72 | CYP3A4 (0.57) | ALDH1A1LMNASMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL21363758 | 0.72 | CYP3A4 (0.63) | ALDH1A1L3MBTL1SMN1; SMN2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354911-B2 | 1,3-benzodioxol compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-04-08 | — | — | US | disclosed |
| US-7354911-B2 | 1,3-benzodioxol compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-04-08 | — | — | US | disclosed |
| US-20070231413-A1 | 1,3-BENZODIOXOL COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070231413-A1 | 1,3-BENZODIOXOL COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070231413-A1 | 1,3-BENZODIOXOL COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070231413-A1 | 1,3-BENZODIOXOL COMPOUND AND USE OF SAME | DDT, BBOX1, PRDX1 | POLB 3359/4885ALDH1A1 488/4885LMNA 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.