Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846362 | 0.94 | LMNA (0.45) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL1276907 | 0.80 | MAPT (0.37) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL14308974 | 0.79 | LMNA (0.46) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL29241858 | 0.78 | SMN1; SMN2 (0.36) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL13409454 | 0.75 | LMNA (0.42) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL12326879 | 0.74 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL18012879 | 0.74 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL5019491 | 0.74 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL1374699 | 0.74 | LMNA (0.44) | LMNAMITFSMN1; SMN2MAPTKMT2A | |
| SCHEMBL11816203 | 0.74 | HTT (0.44) | LMNAMITFSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368586-B2 | Organosilicon compounds with a masked isocyanate group | WACKER CHEMIE AG (DE) | 2008-05-06 | — | — | US | disclosed |
| EP-1771457-B1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | WACKER CHEMIE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| US-20070123644-A1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | WACKER CHEMIE AG (DE) | 2007-05-31 | — | — | US | disclosed |
| EP-1771457-A1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | Wacker Chemie AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006012957-A1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | WACKER CHEMIE AG (DE) | 2006-02-09 | — | — | WO | disclosed |