Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003616 | 0.90 | HTT (0.38) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6259978 | 0.89 | LMNA (0.41) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL19968525 | 0.89 | LMNA (0.41) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL18012879 | 0.87 | LMNA (0.44) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1374699 | 0.87 | LMNA (0.44) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5019491 | 0.87 | LMNA (0.44) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL16151509 | 0.83 | PAOX (0.43) | LMNAMITFSMN1; SMN2USP2KDM4E | |
| SCHEMBL11816203 | 0.83 | HTT (0.44) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL12465216 | 0.83 | LMNA (0.41) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15178109 | 0.83 | LMNA (0.41) | LMNAMITFSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853321-B2 | Laser curable polymerisable composition for the protection of hard tissue | DENTSPLY INTERNATIONAL INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20140058010-A1 | LASER CURABLE POLYMERISABLE COMPOSITION FOR THE PROTECTION OF HARD TISSUE | DENTSPLY INTERNATIONAL INC. (US) | 2014-02-27 | — | — | US | disclosed |
| EP-1771142-B1 | LASER CURABLE POLYMERISABLE DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2011-09-07 | — | — | EP | disclosed |
| US-20080274442-A1 | Laser curable polymerisable composition for the protection of hard tissue | KLEE JOACHIM E | 2008-11-06 | — | — | US | disclosed |
| US-20080274442-A1 | Laser curable polymerisable composition for the protection of hard tissue | KLEE JOACHIM E | 2008-11-06 | — | — | US | disclosed |
| US-20070010597-A1 | Laser curable polymerisable composition for he protection of hard tissue | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2007-01-11 | — | — | US | disclosed |
| US-20070010597-A1 | Laser curable polymerisable composition for he protection of hard tissue | DENTSPLY RESEARCH AND DEVELOPMENT CORP. (US) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274442-A1 | Laser curable polymerisable composition for the protection of hard tissue | HSPA2, CDH1, HSPH1 | LMNA 1198/4885MITF 3864/4885SMN1; SMN2 3200/4885 |
| US-20140058010-A1 | LASER CURABLE POLYMERISABLE COMPOSITION FOR THE PROTECTION OF HARD TISSUE | HSPA2, CDH1, HSPH1 | LMNA 1198/4885MITF 3864/4885SMN1; SMN2 3200/4885 |
| US-20070010597-A1 | Laser curable polymerisable composition for he protection of hard tissue | HSPH1, HEATR1, HSPA2 | LMNA 1391/4885MITF 4281/4885SMN1; SMN2 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.