Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14194568 | 0.85 | CYP26A1 (0.36) | CYP26A1CYP26B1 | |
| SCHEMBL6809650 | 0.81 | CYP26A1 (0.52) | CYP26A1CYP26B1 | |
| SCHEMBL5736584 | 0.71 | CYP26A1 (0.38) | CYP26A1CYP26B1 | |
| SCHEMBL14194562 | 0.69 | RARA (0.34) | CYP26A1CYP26B1 | |
| SCHEMBL5737184 | 0.69 | CYP26A1 (0.38) | CYP26A1CYP26B1 | |
| SCHEMBL5737183 | 0.69 | CYP26A1 (0.56) | CYP26A1CYP26B1 | |
| SCHEMBL5737071 | 0.69 | CYP26A1 (0.38) | CYP26A1CYP26B1 | |
| SCHEMBL14223679 | 0.68 | CYP26A1 (0.54) | CYP26A1CYP26B1 | |
| SCHEMBL5735116 | 0.67 | CYP26A1 (0.44) | CYP26A1CYP26B1 | |
| SCHEMBL4849313 | 0.67 | CYP26A1 (0.42) | CYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351737-B2 | 4-[(8-substituted)-6-chromanoyl]-and 4-[8-substituted)-chroman-6-YL-ethynyl]-benzoic and phenylacetic acids, their esters and salts having cytochrome P450RAI inhibitory activity | ALLERGAN, INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-20030207937-A1 | 4-[(8-Substituted)-6-chromanoyl]-and 4-[8-substituted)-chroman-6-yl-ethynyl]-benzoic and phenylacetic acids, their esters and salts having cytochrome P450RAI inhibitory activity | ALLERGAN, INC. | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207937-A1 | 4-[(8-Substituted)-6-chromanoyl]-and 4-[8-substituted)-chroman-6-yl-ethynyl]-benzoic and phenylacetic acids, their esters and salts having cytochrome P450RAI inhibitory activity | RXRA, RARA, CYP26A1 | CYP26A1 3/4885CYP26B1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.