Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472768 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1POLBLMNA | |
| SCHEMBL11081275 | 0.77 | GLA (0.32) | GLAMAPK1POLB | |
| SCHEMBL651 | 0.75 | PIN1 (0.42) | KDM5BGLAMAPK1POLBHCAR2 | |
| SCHEMBL3025482 | 0.73 | GLA (0.36) | KDM5BGLAPOLBHCAR2PIN1 | |
| SCHEMBL3834785 | 0.71 | CDK4 (0.36) | KDM5BGLAALDH1A1POLBHCAR2 | |
| SCHEMBL2626705 | 0.70 | PIN1 (0.37) | KDM5BGLAMAPK1POLBHCAR2 | |
| SCHEMBL11049418 | 0.70 | GLA (0.33) | GLAALDH1A1POLBLMNAKDM4C | |
| SCHEMBL14959719 | 0.69 | PIN1 (0.36) | KDM5BGLAMAPK1POLBHCAR2 | |
| SCHEMBL14959679 | 0.68 | GLA (0.32) | GLAPOLBHCAR2PIN1 | |
| SCHEMBL8431293 | 0.68 | KDM4E (0.43) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148344-A3 | PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL | MATRIX LAB LTD (IN) | 2008-04-24 | — | — | WO | disclosed |
| WO-2007148344-A2 | PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL | MATRIX LABORATORIES LIMITED (IN) | 2007-12-27 | — | — | WO | disclosed |
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |