Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651 | 0.86 | PIN1 (0.42) | PIN1HCAR2GLARNASEH1KDM5A | |
| SCHEMBL14959719 | 0.86 | PIN1 (0.36) | PIN1HCAR2GLARNASEH1KDM5A | |
| SCHEMBL2626703 | 0.82 | ALDH1A1 (0.42) | POLBCYP1A2MAPK1CYP2C19 | |
| SCHEMBL8431293 | 0.78 | KDM4E (0.43) | CYP1A2MAPK1CYP2C19 | |
| SCHEMBL7914214 | 0.77 | PARP1 (0.40) | PIN1HCAR2MAPK1 | |
| SCHEMBL7300490 | 0.77 | HCAR2 (0.44) | PIN1HCAR2RNASEH1CYP1A2MAPK1 | |
| SCHEMBL9337401 | 0.75 | GPR84 (0.46) | PIN1HCAR2CYP1A2MAPK1CASP1 | |
| SCHEMBL3025482 | 0.75 | GLA (0.36) | PIN1HCAR2GLAKDM5AKDM5B | |
| SCHEMBL14959720 | 0.73 | GLA (0.32) | GLAPOLB | |
| SCHEMBL3834785 | 0.72 | CDK4 (0.36) | PIN1HCAR2GLAKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095237-A1 | Process for the Preparation of 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylates | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2012-04-19 | — | — | US | disclosed |
| US-20120095237-A1 | Process for the Preparation of 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylates | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095237-A1 | Process for the Preparation of 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylates | MED1, ADH1C, ADH1A | PIN1 4559/4885HCAR2 272/4885GLA 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.