Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877504 | 0.91 | KDM4E (0.47) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL3874836 | 0.81 | KDM4E (0.47) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL4846827 | 0.78 | RAB9A (0.35) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL3874539 | 0.78 | RECQL (0.50) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL3872796 | 0.76 | ALDH1A1 (0.52) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL3876483 | 0.72 | KDM4E (0.47) | MAPTKDM4EGAAHSD17B10ALDH1A1 | |
| SCHEMBL30743074 | 0.71 | AHR (0.59) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL2628334 | 0.71 | AHR (0.59) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL3873224 | 0.71 | NQO1 (0.43) | MAPTKDM4EGAAHSD17B10HPGD | |
| SCHEMBL13564024 | 0.70 | DYRK1A (0.49) | MAPTKDM4EGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |