Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874539 | 0.81 | RECQL (0.50) | MAPTGAAKDM4EHTTALDH1A1 | |
| SCHEMBL3877504 | 0.79 | KDM4E (0.47) | MAPTGAAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL3872796 | 0.79 | ALDH1A1 (0.52) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL4846820 | 0.78 | MAPT (0.40) | RAB9AMAPTGAAKDM4EPOLB | |
| SCHEMBL3882591 | 0.71 | RECQL (0.50) | RAB9AMAPTGAAKDM4EHTT | |
| SCHEMBL3878088 | 0.70 | ALDH1A1 (0.52) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL3874836 | 0.69 | KDM4E (0.47) | MAPTGAAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL3873224 | 0.69 | NQO1 (0.43) | RAB9AMAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL4887783 | 0.68 | IGF1R (0.38) | EGFRIGF1RFLT4KDRMAPT | |
| SCHEMBL3880857 | 0.67 | MAOA (0.51) | MAPTGAAKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |