Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841783 | 0.79 | SKP2 (0.73) | PTGS1PTGS2SKP2TSHRTDP1 | |
| SCHEMBL31634603 | 0.79 | SKP2 (0.73) | PTGS1PTGS2SKP2TSHRTDP1 | |
| SCHEMBL3482834 | 0.77 | SKP2 (0.70) | PTGS1PTGS2SKP2TAAR1TSHR | |
| SCHEMBL4846933 | 0.75 | ATM (0.49) | PTGS1PTGS2TAAR1L3MBTL1TDP1 | |
| SCHEMBL21236814 | 0.73 | PTGS1 (0.58) | PTGS1PTGS2TAAR1L3MBTL1TRPM8 | |
| Ammonia Solution, Strong SCHEMBL4846523 | 0.73 | SKP2 (0.56) | SKP2TSHRTDP1ALDH1A1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL5929377 | 0.72 | SKP2 (0.63) | PTGS1SKP2TAAR1ADRA2ATSHR | |
| SCHEMBL3514830 | 0.72 | SKP2 (0.81) | SKP2TSHRTDP1ALDH1A1CYP3A4 | |
| SCHEMBL6297863 | 0.71 | L3MBTL1 (0.54) | L3MBTL1TSHRLMNATDP1ALDH1A1 | |
| SCHEMBL21622793 | 0.71 | LMNA (0.61) | PTGS1PTGS2TAAR1L3MBTL1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | claimed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | claimed |
| US-20060005320-A1 | N-alkylheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1589012-A2 | N-alkylheteroaryl secondary para-phenyldiamine, dyeing composition containing the same, process for making it and uses thereof | L'OREAL (FR) | 2005-10-26 | — | — | EP | claimed |
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | disclosed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | KRT18, CDC73, PRKDC | PTGS1 4573/4885PTGS2 4543/4885SKP2 2385/4885 |
| US-20060005320-A1 | N-alkylheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | KRT18, CDC73, PRKDC | PTGS1 4573/4885PTGS2 4543/4885SKP2 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.