Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.62 |
| ▸ | CCR2 | P41597 | 8/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847104 | 1.00 | SIGMAR1 (0.62) | SIGMAR1CCR2BACE1BCHEACHE | |
| SCHEMBL4426840 | 0.88 | CCR2 (0.65) | SIGMAR1CCR2DRD4 | |
| SCHEMBL4846218 | 0.88 | CCR2 (0.65) | SIGMAR1CCR2DRD4 | |
| SCHEMBL4426833 | 0.88 | CCR2 (0.65) | SIGMAR1CCR2DRD4 | |
| SCHEMBL4840965 | 0.87 | CCR2 (0.64) | SIGMAR1CCR2BACE1BCHEACHE | |
| SCHEMBL4840950 | 0.87 | CCR2 (0.64) | SIGMAR1CCR2BACE1BCHEACHE | |
| Hydrochloric Acid SCHEMBL31462269 | 0.86 | SIGMAR1 (0.65) | SIGMAR1CCR2BACE1DRD4 | |
| SCHEMBL5434322 | 0.84 | SIGMAR1 (0.58) | SIGMAR1CCR2BACE1BCHEACHE | |
| SCHEMBL4591750 | 0.84 | SIGMAR1 (0.58) | SIGMAR1CCR2BACE1BCHEACHE | |
| SCHEMBL5421451 | 0.84 | SIGMAR1 (0.58) | SIGMAR1CCR2BACE1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |