Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.57 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421451 | 1.00 | SIGMAR1 (0.58) | SIGMAR1LTA4HBCHEACHEBACE1 | |
| SCHEMBL4591750 | 1.00 | SIGMAR1 (0.58) | SIGMAR1LTA4HBCHEACHEBACE1 | |
| SCHEMBL4591127 | 0.92 | KMT2A (0.56) | SIGMAR1LTA4HBCHEACHEBACE1 | |
| SCHEMBL4592089 | 0.92 | SIGMAR1 (0.68) | SIGMAR1LTA4HCCR5DRD4TEAD1 | |
| SCHEMBL7500995 | 0.86 | DRD4 (0.67) | SIGMAR1LTA4HBCHEACHEBACE1 | |
| SCHEMBL7393471 | 0.86 | DRD4 (0.67) | SIGMAR1LTA4HBCHEACHEBACE1 | |
| SCHEMBL1781392 | 0.86 | DRD4 (0.67) | SIGMAR1LTA4HBCHEACHEBACE1 | |
| SCHEMBL12387529 | 0.85 | LTA4H (0.57) | LTA4HCCR2DRD4DRD2TEAD1 | |
| SCHEMBL12355214 | 0.85 | LTA4H (0.57) | LTA4HBCHEACHEBACE1CCR2 | |
| SCHEMBL4847104 | 0.84 | SIGMAR1 (0.62) | SIGMAR1BCHEACHEBACE1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070111981-A1 | New (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | ROTH GERALD J | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111981-A1 | New (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, GPR119, MCHR2 | SIGMAR1 59/4885LTA4H 1868/4885BCHE 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.