SCHEMBL4847809

SCHEMBL4847809

c1ccc2c(c1)ccc1c3c4c(ccc5cccc(c54)C3)cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
CYP1A2 P05177 6/20 0.51
FYN P06241 2/20 0.51
ACHE P22303 2/20 0.51
AHR P35869 2/20 0.51
LCK P06239 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
MAPT P10636 1/20 0.51
SLC6A2 P23975 1/20 0.51
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
ERBB2 P04626 1/20 0.47
MAOA P21397 1/20 0.47
HSD17B10 Q99714 4/20 0.42
CYP1B1 Q16678 2/20 0.42
HIF1A Q16665 1/20 0.42
HPRT1 P00492 4/20 0.41
CYP2A6 P11509 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598416 0.85 TSHR (0.55) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4845361 0.83 TSHR (0.53) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4846290 0.83 TSHR (0.53) ALDH1A1CYP1A2FYNACHEAHR
Cholanthrene SCHEMBL9048 0.79 ALDH1A1 (0.65) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4856741 0.75 TSHR (0.57) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4852107 0.75 TSHR (0.61) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4854444 0.73 TSHR (0.59) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4852765 0.73 CYP1A2 (0.55) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4847355 0.73 CYP1A2 (0.77) ALDH1A1CYP1A2FYNACHEAHR
SCHEMBL4847418 0.73 CYP1A2 (0.77) ALDH1A1CYP1A2FYNACHEAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed