Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.56 |
| ▸ | CES1 | P23141 | 7/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196818 | 0.90 | CES2 (0.52) | CES2CES1APPAKR1C2AKR1C1 | |
| SCHEMBL6142583 | 0.90 | CES2 (0.45) | CES2CES1APPAKR1C2AKR1C1 | |
| SCHEMBL6673707 | 0.86 | CES2 (0.52) | CES2CES1APPHNF4AFFAR1 | |
| SCHEMBL6675223 | 0.85 | CES2 (0.68) | CES2CES1APPFFAR1FFAR4 | |
| SCHEMBL5533189 | 0.85 | FFAR1 (0.49) | CES2CES1HNF4AFFAR1 | |
| SCHEMBL4367063 | 0.83 | APP (0.52) | APPAKR1C2AKR1C1HNF4AFFAR1 | |
| SCHEMBL2336741 | 0.83 | CES2 (0.71) | CES2CES1APPFFAR1RAB9A | |
| SCHEMBL3753633 | 0.83 | CES2 (0.64) | CES2CES1APPHNF4AFFAR1 | |
| SCHEMBL4190711 | 0.82 | CES2 (0.58) | CES2CES1APPHNF4AFFAR1 | |
| SCHEMBL13582217 | 0.80 | FFAR1 (0.46) | CES2CES1APPHNF4AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493183-B1 | PROCESS FOR MAKING AIR GAP CONTAINING SEMICONDUCTING DEVICES AND RESULTING SEMICONDUCTING DEVICE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-05 | — | — | EP | disclosed |
| US-7381850-B2 | Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20060267000-A1 | Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2006-11-30 | — | — | US | disclosed |
| US-6946382-B2 | Process for making air gap containing semiconducting devices and resulting semiconducting device | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050124172-A1 | Process for making air gap containing semiconducting devices and resulting semiconducting device | DOW GLOBAL TECHNOLOGIES LLC | 2005-06-09 | — | — | US | disclosed |
| EP-1493183-A2 | PROCESS FOR MAKING AIR GAP CONTAINING SEMICONDUCTING DEVICES AND RESULTING SEMICONDUCTING DEVICE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2004089862-A2 | MULTIFUNCTIONAL UNSYMMETRICALLY SUBSTITUTED MONOMERS AND POLYARYLENE COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| WO-2003085719-A2 | PROCESS FOR MAKING AIR GAP CONTAINING SEMICONDUCTING DEVICES AND RESULTING SEMICONDUCTING DEVICE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060267000-A1 | Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom | WASF2, DDT, CAD | CES2 1963/4885CES1 4150/4885APP 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.