⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850260 | 0.79 | DUT (0.30) | — | |
| SCHEMBL4847630 | 0.77 | — | — | |
| SCHEMBL12361335 | 0.69 | — | — | |
| SCHEMBL9045350 | 0.68 | DUT (0.35) | — | |
| SCHEMBL14271891 | 0.68 | — | — | |
| SCHEMBL31644722 | 0.68 | DUT (0.36) | — | |
| SCHEMBL6393715 | 0.68 | DUT (0.36) | — | |
| SCHEMBL28698317 | 0.68 | DUT (0.36) | — | |
| SCHEMBL3605071 | 0.68 | DUT (0.36) | — | |
| SCHEMBL1578618 | 0.67 | DUT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188651-A1 | Analogs of dictyostatin, intermediates therefor and methods of systhesis thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-08-07 | — | — | US | disclosed |
| US-7321046-B2 | Analogs of dictyostatin, intermediates therefor and methods of synthesis thereof | UNIVERSITY OF PITTSBURGH (US) | 2008-01-22 | — | — | US | disclosed |
| US-20060025395-A1 | Analogs of dictyostatin, intermediates therefor and methods of synthesis thereof | PITTSBURGH, UNIVERSITY OF | 2006-02-02 | — | — | US | disclosed |