Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7556226 | 0.98 | LMNA (0.44) | LMNAHTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11067593 | 0.90 | GAA (0.45) | LMNAHTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11069688 | 0.88 | ACHE (0.45) | LMNAHTTSMN1; SMN2KDM4EMEN1 | |
| Sulfuric Acid SCHEMBL9352881 | 0.85 | ACHE (0.44) | KDM4EKMT2AALDH1A1GAAHPGD | |
| SCHEMBL29462670 | 0.83 | ACHE (0.43) | KDM4EKMT2AALDH1A1GAAHPGD | |
| SCHEMBL11073869 | 0.83 | ACHE (0.43) | KDM4EKMT2AALDH1A1GAAHPGD | |
| Sulfuric Acid SCHEMBL9352888 | 0.82 | ACHE (0.42) | KDM4EMEN1KMT2ATERTALDH1A1 | |
| SCHEMBL11847896 | 0.81 | LMNA (0.40) | LMNAHTTSMN1; SMN2KDM4EMEN1 | |
| 1-Ethylquinolonium SCHEMBL11069884 | 0.81 | KDM4E (0.50) | LMNAHTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL1001565 | 0.80 | KDM4E (0.46) | LMNAHTTSMN1; SMN2KDM4ETERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220008307-A1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | HENKEL AG & CO. KGAA (DE) | 2022-01-13 | — | — | US | claimed |
| EP-3873407-A1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | Henkel AG & Co. KGaA (DE) | 2021-09-08 | — | — | EP | claimed |
| US-4431774-A | QUINOLINIUM SULFONATES AS LATENT ACID CATALYSTS; RADIATION; DECOMPOSITION; STORAGE STABILITY | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | claimed |
| US-20220008307-A1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | HENKEL AG & CO. KGAA (DE) | 2022-01-13 | — | — | US | disclosed |
| EP-3873407-A1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | Henkel AG & Co. KGaA (DE) | 2021-09-08 | — | — | EP | disclosed |
| US-7378240-B2 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY(dA-dT)]2 binders | LIGHT UP TECHNOLOGIES AB (SE) | 2008-05-27 | — | — | US | disclosed |
| EP-1773289-A1 | BLEACHING AGENTS COMPRISING CARBONIC ACID DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006018089-A1 | OXIDATION COLORANTS COMPRISING DIAMINOBENZENE DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-02-23 | — | — | WO | disclosed |
| WO-2005123021-A1 | BLEACHING AGENTS COMPRISING CARBONIC ACID DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-29 | — | — | WO | disclosed |
| EP-1390433-B1 | SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF POLY(DA-DT)] 2 BINDERS | LIGHT UP TECHNOLOGIES AB (SE) | 2005-02-16 | — | — | EP | disclosed |
| US-20040132046-A1 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY (dA-dT)]2 binders | LIGHT UP TECHNOLOGIES AB (SE) | 2004-07-08 | — | — | US | disclosed |
| EP-1390433-A1 | SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF POLY(DA-DT)] 2 BINDERS | Light Up Technologies AB (SE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002090443-A1 | SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF [POLY(DA-DT)]2 BINDERS | LIGHT UP TECHNOLOGIES AB (SE) | 2002-11-14 | — | — | WO | disclosed |
| US-4431774-A | QUINOLINIUM SULFONATES AS LATENT ACID CATALYSTS; RADIATION; DECOMPOSITION; STORAGE STABILITY | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| US-3966720-A | Process for producing desacetoxy cephalosporanic acid compound | NIKKEN CHEMICALS CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220008307-A1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | KRT18, ALPG, AR | LMNA 2211/4885HTT 1185/4885SMN1; SMN2 3158/4885 |
| US-20040132046-A1 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY (dA-dT)]2 binders | DRD4, FUT4, DRD1 | LMNA 3593/4885HTT 777/4885SMN1; SMN2 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.