SCHEMBL4848752

SCHEMBL4848752

C[Si](C)(Cl)c1ccc(CCl)cc1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10814635 0.85 CA1 (0.37) CA1CA2ESR1
SCHEMBL3470794 0.82 CA1 (0.38) CA1CA2ESR1
SCHEMBL705667 0.81 ALDH1A1 (0.36) ESR1
SCHEMBL3482281 0.80 TP53 (0.42) CA2
SCHEMBL937352 0.79 CA1 (0.39) CA1CA2
SCHEMBL27786246 0.78 HRH3 (0.46) CA1CA2
SCHEMBL8850274 0.75 LMNA (0.33)
SCHEMBL15453502 0.75 CA1 (0.33) CA1CA2
SCHEMBL97582 0.74 CA1 (0.52) CA1CA2ESR1
SCHEMBL9812193 0.73 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7463400-B1 Electrochromic display device FUJI XEROX CO., LTD. (JP) 2008-12-09 US disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed