SCHEMBL705667

SCHEMBL705667

C[Si](C)(Cl)c1ccc([Si](C)(C)Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL801429 0.90
SCHEMBL10318540 0.90 NR1H2 (0.41)
SCHEMBL80628 0.87 ACHE (0.47) ALDH1A1HPGD
SCHEMBL7913246 0.87 LMNA (0.47) ALDH1A1
SCHEMBL10317698 0.85 CYP2A6 (0.44) ALDH1A1HPGD
SCHEMBL1599765 0.85 ACHE (0.41)
SCHEMBL7636718 0.85 IDO1 (0.41)
SCHEMBL68909 0.83 ESR1 (0.44) ALDH1A1ESR1ESR2
SCHEMBL9292117 0.83 ESR1 (0.38) ESR1
Methane SCHEMBL6673779 0.81 ESR1 (0.42) ALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955905-A Vinyl modified organic silicon resin and preparation method and application thereof 常州市嘉诺有机硅有限公司 2024-11-15 CN claimed
US-20070026667-A1 Composition for forming etching stopper layer TASHIRO YUJI 2007-02-01 US claimed
US-5318848-A Surface modified with a multi-legged silane-coupling agent SHISEIDO COMPANY LTD. (JP) 1994-06-07 US claimed
EP-0470255-B1 CHROMATOGRAPHIC PACKING AND PREPARATION THEREOF SHISEIDO CO LTD (JP) 1994-06-01 EP claimed
EP-0470255-A1 CHROMATOGRAPHIC PACKING AND PREPARATION THEREOF SHISEIDO COMPANY LIMITED (JP) 1992-02-12 EP claimed
US-4709054-A REACTION OF AROMATIC ACYL HALIDE AND HALOGENATED POLYSILANE, TRANSITION METAL CATALYST GENERAL ELECTRIC COMPANY (US) 1987-11-24 US claimed
JP-8245880-A None JP disclosed
CN-118955905-A Vinyl modified organic silicon resin and preparation method and application thereof 常州市嘉诺有机硅有限公司 2024-11-15 CN disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11485805-B2 Poly(meth)acrylate, and coating composition and coated article containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-11-01 US disclosed
EP-3647330-B1 POLY(METH)ACRYLATE, AND COATING COMPOSITION AND COATED ARTICLE CONTAINING SAME SHINETSU CHEMICAL CO (JP) 2022-07-27 EP disclosed
US-11292890-B2 Curable resin composition and sealing material using same NIPPON SHOKUBAI CO., LTD. (JP) 2022-04-05 US disclosed
EP-0284873-A2 Silylation method GENERAL ELECTRIC COMPANY (US) 1988-10-05 EP disclosed
US-4766037-A Photodegradable microcapsules FUJI PHOTO FILM CO., LTD. (JP) 1988-08-23 US disclosed
US-4739089-A Acylation of polysilylaromatic organic compounds and products obtained therefrom GENERAL ELECTRIC COMPANY (US) 1988-04-19 US disclosed
US-4709054-A REACTION OF AROMATIC ACYL HALIDE AND HALOGENATED POLYSILANE, TRANSITION METAL CATALYST GENERAL ELECTRIC COMPANY (US) 1987-11-24 US disclosed
US-4604477-A Method for making silylaroylhalides and reaction products GENERAL ELECTRIC COMPANY (US) 1986-08-05 US disclosed
US-4563514-A Curable polysilarylene-polysiloxane copolymers GENERAL ELECTRIC COMPANY (US) 1986-01-07 US disclosed
US-4435587-A REACTION OF A SILICON HALIDE COMPOUND WITH AN ISOCYANATE OR CYANATE MATSUMOTO SEIYAKU KOGYO KABUSHIKI KAISHA (JP) 1984-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 ALDH1A1 2097/4885ESR1 4503/4885ESR2 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.