Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841588 | 0.91 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1MAPTRXFP1HDAC1 | |
| SCHEMBL4848474 | 0.88 | CYP4F2 (0.39) | CYSLTR2CYSLTR1LTB4RPPARGPPARA | |
| SCHEMBL10290027 | 0.74 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL10290026 | 0.74 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL14297620 | 0.73 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL1197247 | 0.71 | MAPT (0.78) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL31584693 | 0.70 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL765727 | 0.69 | SMN1; SMN2 (0.58) | CYSLTR2CYSLTR1MAPTRXFP1HDAC3 | |
| SCHEMBL8849634 | 0.69 | LTB4R (0.60) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL2745021 | 0.68 | LTA4H (0.38) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| CN-101070316-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARMA GMBH (DE) | 2007-11-14 | — | — | CN | disclosed |
| CN-1331862-C | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (DE) | 2007-08-15 | — | — | CN | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |