Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | TACR3 | P29371 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848837 | 0.88 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PPARGPPARALTB4R | |
| SCHEMBL8796135 | 0.85 | TSHR (0.34) | CYSLTR1 | |
| SCHEMBL4841588 | 0.85 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1PPARGPPARA | |
| SCHEMBL8795978 | 0.80 | TRPA1 (0.32) | — | |
| SCHEMBL4841791 | 0.78 | HTR2C (0.40) | — | |
| SCHEMBL8794946 | 0.77 | ENPP2 (0.35) | — | |
| SCHEMBL8149465 | 0.76 | ADRB1 (0.41) | — | |
| SCHEMBL2745021 | 0.73 | LTA4H (0.38) | PPARGPPARALTA4H | |
| SCHEMBL8796366 | 0.73 | IDO1 (0.42) | — | |
| SCHEMBL6622199 | 0.73 | MAOB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| CN-101070316-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARMA GMBH (DE) | 2007-11-14 | — | — | CN | disclosed |
| CN-1331862-C | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (DE) | 2007-08-15 | — | — | CN | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |
| CN-1349525-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (BE) | 2002-05-15 | — | — | CN | disclosed |
| EP-1177187-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064888-A1 | DI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |