Sugi Predict

Sugi Predict / Compounds / SCHEMBL4849304

SCHEMBL4849304

SCHEMBL4849304

CCOC(=O)C(Sc1ccc(OCCn2c(CC)nc(-c3ccccc3)cc2=O)cc1)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CPB1 P15086 1/20 0.42
▸ ALOX5 P09917 3/20 0.37
▸ PPARG P37231 2/20 0.37
▸ PPARA Q07869 2/20 0.37
▸ PTGES O14684 1/20 0.37
▸ KMT2A Q03164 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ GSK3B P49841 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ FAAH O00519 2/20 0.35
▸ PDE10A Q9Y233 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14263912 0.92 PPARG (0.43) ALOX5PPARGPPARAPTGESKMT2A
SCHEMBL4855146 0.89 SMN1; SMN2 (0.44) ALOX5PPARGPPARAPTGESALDH1A1
SCHEMBL4858357 0.86 MAPT (0.35) CPB1KMT2AMAPTTDP1ALDH1A1
SCHEMBL4859967 0.83 ELANE (0.38) PPARGPPARAMAPTTDP1GSK3B
SCHEMBL14263926 0.82 LMNA (0.43) PPARGKMT2AMAPTALDH1A1TSHR
SCHEMBL4850885 0.81 PPARG (0.39) PPARGPPARATDP1GSK3BRXFP1
SCHEMBL5659043 0.80 PPARA (0.52) PPARGPPARA
SCHEMBL4849238 0.80 P2RY12 (0.39) PPARGPPARAMAPTTDP1GSK3B
SCHEMBL4854217 0.79 ATP4A (0.37) PPARGPPARAGSK3BFAAH
SCHEMBL4861486 0.79 PPARA (0.44) PPARGPPARAGSK3BRXFP1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348334-B2 Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2008-03-25 — — US disclosed
US-7348334-B2 Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LIMITED (IN) 2008-03-25 — — US disclosed
US-20030013729-A1 New monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES LTD. 2003-01-16 — — US disclosed
WO-2002081454-A1 DERIVATIVES OF ARYL ACIDS, THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2002-10-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030013729-A1 New monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them GPR119, FFAR1, FFAR3 CPB1 3415/4885ALOX5 79/4885PPARG 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.