Ribose (Furanose)

Ribose (Furanose)

SCHEMBL4850611

OC[C@H]1O[C@@H](O)[C@H](O)[C@@H]1O.Oc1c[nH]c2ccccc12

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.59
▸ ADORA2A P29274 3/20 0.43
▸ ADORA2B P29275 3/20 0.43
▸ ADORA3 P0DMS8 3/20 0.43
▸ ADORA1 P30542 3/20 0.43
▸ SLC5A2 P31639 2/20 0.41
▸ CYP3A4 P08684 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ AHR P35869 1/20 0.40
▸ GPR84 Q9NQS5 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ EPHX2 P34913 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribose (Furanose) SCHEMBL3283323 1.00 ATM (0.59) ATMADORA2AADORA2BADORA3ADORA1
D-Galactose SCHEMBL14975826 0.99 ATM (0.61) ATMADORA2AADORA2BADORA3ADORA1
B-D-Galactose SCHEMBL15283666 0.99 ATM (0.61) ATMADORA2AADORA2BADORA3ADORA1
Beta-D-Glucose SCHEMBL4850633 0.99 ATM (0.61) ATMADORA2AADORA2BADORA3ADORA1
Dextrose SCHEMBL14975069 0.99 ATM (0.61) ATMADORA2AADORA2BADORA3ADORA1
B-D-Galactose SCHEMBL27938187 0.99 ATM (0.61) ATMADORA2AADORA2BADORA3ADORA1
D-Mannose SCHEMBL14975436 0.99 ATM (0.61) ATMADORA2AADORA2BADORA3ADORA1
B-D-Galactose SCHEMBL27919540 0.81 GPR84 (0.46) ATMADORA2AADORA2BADORA3ADORA1
B-D-Galactose SCHEMBL27848029 0.81 ADORA3 (0.46) ATMADORA2AADORA2BADORA3ADORA1
B-D-Galactose SCHEMBL27919543 0.80 ATM (0.44) ATMADORA2AADORA2BADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323488-B2 Chromogenic enzyme substrates BURTON MICHAEL 2008-01-29 — — US claimed
EP-1436411-B1 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2005-12-14 — — EP claimed
US-20050124556-A1 Chromogenic enzyme substrates BURTON MICHAEL (GB) 2005-06-09 — — US claimed
EP-1436411-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY Burton, Michael (GB) 2004-07-14 — — EP claimed
WO-2003035896-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 — — WO claimed
US-7323488-B2 Chromogenic enzyme substrates BURTON MICHAEL 2008-01-29 — — US disclosed
US-7323488-B2 Chromogenic enzyme substrates BURTON MICHAEL 2008-01-29 — — US disclosed
EP-1436411-B1 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2005-12-14 — — EP disclosed
US-20050124556-A1 Chromogenic enzyme substrates BURTON MICHAEL (GB) 2005-06-09 — — US disclosed
US-20050124556-A1 Chromogenic enzyme substrates BURTON MICHAEL (GB) 2005-06-09 — — US disclosed
EP-1436411-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY Burton, Michael (GB) 2004-07-14 — — EP disclosed
WO-2003035896-A3 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2004-04-22 — — WO disclosed
WO-2003035896-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 — — WO disclosed
WO-2003035896-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124556-A1 Chromogenic enzyme substrates DCXR, MGAM, IDE ATM 3705/4885ADORA2A 2273/4885ADORA2B 2584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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