Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.68 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.61 |
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH4 | P08319 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14332259 | 1.00 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2EPHX1CASP2ADH1B | |
| SCHEMBL23505654 | 1.00 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2EPHX1CASP2ADH1B | |
| SCHEMBL13645782 | 1.00 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2EPHX1CASP2ADH1B | |
| SCHEMBL23505697 | 1.00 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2EPHX1CASP2ADH1B | |
| SCHEMBL4855151 | 0.98 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2EPHX1CASP2ADH1B | |
| SCHEMBL4855765 | 0.91 | — | — | |
| SCHEMBL1700721 | 0.84 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2EPHX1CASP2NAAA | |
| SCHEMBL444526 | 0.84 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2EPHX1CASP2NAAA | |
| SCHEMBL2530353 | 0.84 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2EPHX1CASP2NAAA | |
| SCHEMBL6131120 | 0.84 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2EPHX1CASP2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355074-B2 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | THE UNIVERSITY OF MARYLAND (US) | 2008-04-08 | — | — | US | disclosed |
| US-20050009921-A1 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | MARYLAND, UNIVERSITY OF | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009921-A1 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | SLC26A3, SLC22A8, SLC43A1 | ZDHHC20 427/4885ZDHHC2 449/4885EPHX1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.