SCHEMBL4851033

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4861078	0.77	RXRA (0.35)	RXRAPPARGRARGRARARXRB
	SCHEMBL10212529	0.68	RXRA (0.46)	RXRAPPARGRARGRARARXRB
	SCHEMBL4850986	0.68	RXRA (0.41)	RXRAPPARGRARGRARARXRB
	SCHEMBL961701	0.67	ALDH1A1 (0.52)	HPGDSMN1; SMN2NPSR1CA12CA9
	SCHEMBL19322250	0.65	POLB (0.39)	RXRAPPARGRARGL3MBTL1POLB
	SCHEMBL31063327	0.65	THRB (0.39)	RXRAPPARGRARGSMN1; SMN2POLB
	SCHEMBL4586917	0.65	RXRA (0.51)	RXRAPPARGRARGRARARXRB
	SCHEMBL1539232	0.65	MAPT (0.46)	HPGDNPSR1POLBLMNAMEN1
	SCHEMBL15145489	0.65	HPGD (0.46)	HPGDNPSR1LMNAMEN1MAPT
	SCHEMBL1173265	0.65	MEN1 (0.49)	SMN1; SMN2NPSR1LMNAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.