SCHEMBL4851448

SCHEMBL4851448

CC(C)Cc1ccccc1OB(O)O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.47
GABRB2 P47870 2/20 0.47
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
ELANE P08246 1/20 0.35
ENPP2 Q13822 1/20 0.34
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25173753 0.79 TSHR (0.38) CTSKKMT2A
SCHEMBL30366533 0.79 L3MBTL1 (0.48) GABRA1GABRB2HPGDENPP2ORAI1
SCHEMBL2126532 0.79 L3MBTL1 (0.48) GABRA1GABRB2HPGDENPP2ORAI1
SCHEMBL9014978 0.79 ENPP2 (0.33) HPGDENPP2ORAI1ORAI2ORAI3
SCHEMBL363627 0.79 GABRA1 (0.52) GABRA1GABRB2HPGDHTTCTSS
SCHEMBL30738550 0.79 ENPP2 (0.33) HPGDENPP2ORAI1ORAI2ORAI3
SCHEMBL20543490 0.78 TSHR (0.37) CTSKKMT2A
SCHEMBL20543373 0.78 TSHR (0.37) CTSKKMT2A
SCHEMBL4575612 0.78 GABRA1 (0.50) GABRA1GABRB2HPGDHTTCTSS
SCHEMBL878976 0.76 IDO1 (0.53) GABRA1GABRB2HPGDHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410925-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-08-12 US disclosed
US-7008897-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
US-20060030480-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-09 US disclosed
US-20040209763-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed