Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | SCN2B | O60939 | 2/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269328 | 1.00 | CTSK (0.40) | CTSKHTTNOTUMCYP2C19CYP1A2 | |
| SCHEMBL4857558 | 0.80 | SCN2B (0.44) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4857564 | 0.80 | SCN2B (0.44) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL14269331 | 0.79 | ALDH1A1 (0.40) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4850390 | 0.79 | ALDH1A1 (0.40) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4852106 | 0.79 | NOTUM (0.46) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4852112 | 0.79 | NOTUM (0.46) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4850388 | 0.79 | ALDH1A1 (0.40) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4858973 | 0.78 | SCN2B (0.43) | HTTNOTUMCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL4858968 | 0.78 | SCN2B (0.43) | HTTNOTUMCYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329757-B2 | Substituted iminoazines | BAYER AKTIENGESELLSCHAFT (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7186834-B2 | Substituted iminoazines | BAYER AKTIENGESELLSCHAFT (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20060122062-A1 | Substituted iminoazines | MULLER KLAUS-HELMUT | 2006-06-08 | — | — | US | disclosed |
| US-20040029881-A1 | Substituted iminoazines | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-1286968-A2 | SUBSTITUTED IMINOAZINES | Bayer Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001090071-A2 | SUBSTITUTED IMINOAZINES USED AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122062-A1 | Substituted iminoazines | IDH2, DDT, CYP1A2 | CTSK 4537/4885HTT 1976/4885NOTUM 1583/4885 |
| US-20040029881-A1 | Substituted iminoazines | CYP4Z1, DDT, CYP1A1 | CTSK 4420/4885HTT 2198/4885NOTUM 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.