Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4855225 | 0.85 | DRD2 (0.57) | DRD2ADRA1ALMNASMN1; SMN2 | |
| SCHEMBL4854957 | 0.84 | DRD2 (0.64) | DRD2ADRA1ALTA4HGALR3RAB9A | |
| Hydrochloric Acid SCHEMBL4855743 | 0.83 | DRD2 (0.63) | DRD2ADRA1ALMNATP53LTA4H | |
| SCHEMBL4853485 | 0.83 | DRD2 (0.63) | DRD2ADRA1ATP53LTA4HGALR3 | |
| SCHEMBL4847512 | 0.83 | DRD2 (0.71) | DRD2ADRA1A | |
| Hydrochloric Acid SCHEMBL4854584 | 0.83 | DRD2 (0.62) | DRD2ADRA1ALMNATP53LTA4H | |
| Hydrochloric Acid SCHEMBL4854617 | 0.83 | DRD2 (0.62) | DRD2ADRA1ATP53LTA4HGALR3 | |
| SCHEMBL4615443 | 0.83 | DRD2 (0.50) | DRD2ADRA1ATGM2LMNASMN1; SMN2 | |
| SCHEMBL4847362 | 0.82 | DRD2 (0.58) | DRD2ADRA1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4854154 | 0.82 | DRD2 (0.61) | DRD2ADRA1ALTA4HGALR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446204-B2 | Amino substituted aryloxybenzylpiperidine derivatives | H. LUNDBECK A/S (DK) | 2008-11-04 | — | — | US | disclosed |
| US-20060079522-A1 | Amino substituted aryloxybenzylpiperidine derivatives | H. LUNDBECK A/S (DK) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079522-A1 | Amino substituted aryloxybenzylpiperidine derivatives | MCHR1, MCHR2, MC4R | DRD2 192/4885ADRA1A 38/4885TGM2 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.