Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853190 | 1.00 | CA12 (0.62) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1576809 | 0.89 | CA12 (0.78) | CA12CA1CA2CA3CA4 | |
| SCHEMBL4847121 | 0.84 | FCER2 (0.58) | CA12CA1CA2CA3CA4 | |
| SCHEMBL4847134 | 0.84 | FCER2 (0.58) | CA12CA1CA2CA3CA4 | |
| SCHEMBL4847211 | 0.82 | CA12 (0.60) | CA12CA1CA2CA3CA4 | |
| SCHEMBL4847214 | 0.82 | CA12 (0.60) | CA12CA1CA2CA3CA4 | |
| SCHEMBL464916 | 0.79 | CA12 (0.78) | CA12CA1CA2CA3CA4 | |
| SCHEMBL464917 | 0.79 | CA12 (0.78) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11985033 | 0.79 | CTSS (0.79) | CA12CA1CA2CA3CA4 | |
| SCHEMBL12988928 | 0.79 | CTSS (0.48) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317129-B2 | Chemical synthesis of reagents for peptide coupling | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-08 | — | — | US | disclosed |
| EP-1534718-A4 | CHEMICAL SYNTHESIS OF REAGENTS FOR PEPTIDE COUPLING | WISCONSIN ALUMNI RES FOUND (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20060025578-A1 | Phosphine-borane complexes in the formation of amide bonds between an amino acid, a peptide, or a protein; peptide ligation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-02-02 | — | — | US | disclosed |
| US-6974884-B2 | Improved methods for synthesis of phosphinothiol reagents and novel protected reagents for use in peptide ligation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-12-13 | — | — | US | disclosed |
| EP-1534718-A1 | CHEMICAL SYNTHESIS OF REAGENTS FOR PEPTIDE COUPLING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040030105-A1 | Chemical synthesis of reagents for peptide coupling | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-12 | — | — | US | disclosed |
| WO-2003104243-A1 | CHEMICAL SYNTHESIS OF REAGENTS FOR PEPTIDE COUPLING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2003-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025578-A1 | Phosphine-borane complexes in the formation of amide bonds between an amino acid, a peptide, or a protein; peptide ligation | PTMS, BCAT1, PEBP1 | CA12 1026/4885CA1 677/4885CA2 1188/4885 |
| US-20040030105-A1 | Chemical synthesis of reagents for peptide coupling | PTMS, QPCT, BCAT1 | CA12 706/4885CA1 600/4885CA2 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.