SCHEMBL4853271

SCHEMBL4853271

C[CH]C(=O)OC(C)OCC

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.31
HCAR2 Q8TDS4 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2897717 0.84 LMNA (0.48) LMNATHRBHCAR2
SCHEMBL2898080 0.84 LMNA (0.48) LMNATHRBHCAR2
SCHEMBL1069988 0.83 LMNA (0.42) LMNAHCAR2
SCHEMBL1069990 0.83 LMNA (0.42) LMNAHCAR2
SCHEMBL147629 0.81 TSHR (0.45) LMNATHRB
SCHEMBL8895998 0.80 ATM (0.42) LMNAHCAR2
SCHEMBL4880509 0.78 HCAR2 (0.59) LMNAHCAR2
Fluoromethane SCHEMBL27653465 0.78 TSHR (0.42) LMNATHRB
SCHEMBL8894129 0.78 LMNA (0.41) LMNA
SCHEMBL2897728 0.78 HCAR2 (0.59) LMNAHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684287-A1 Water insoluble red monoazo dyes, their preparation and the use thereof HOECHST MITSUBISHI KASEI CO., LTD. (JP) 1995-11-29 EP claimed
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF SE (DE) 2019-03-26 US disclosed
EP-2668156-B1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2018-10-31 EP disclosed
US-9310677-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF (DE) 2016-04-12 US disclosed
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2016-03-03 US disclosed
EP-2668156-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-12-04 EP disclosed
US-20130308219-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-11-21 US disclosed
WO-2012101245-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2012-08-02 WO disclosed
US-7329694-B2 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-02-12 US disclosed
EP-1445641-A1 OCULAR LENS Johnson & Johnson Vision Care, Inc. (US) 2004-08-11 EP disclosed
EP-1424339-A1 MONOMERS, POLYMERS AND OPHTHALMIC LENSES Johson & Johnson Vision Care Inc. (US) 2004-06-02 EP disclosed
EP-1137641-A1 PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-10-04 EP disclosed
WO-2000034249-A1 PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-15 WO disclosed
WO-2000021936-A1 URACIL HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-20 WO disclosed
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed
EP-0684287-A1 Water insoluble red monoazo dyes, their preparation and the use thereof HOECHST MITSUBISHI KASEI CO., LTD. (JP) 1995-11-29 EP disclosed
EP-0684287-A1 Water insoluble red monoazo dyes, their preparation and the use thereof HOECHST MITSUBISHI KASEI CO., LTD. (JP) 1995-11-29 EP disclosed
US-4769449-A Red mono-azo water-soluble dye containing cyano, amide and amino substituents CASSELLA AKTIENGESELLSCHAFT (DE) 1988-09-06 US disclosed
US-4621136-A Phenyl azo cyanothienyl azo anilino dyestuffs MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1986-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent SULT1E1, COX6B1, SULT1A1 LMNA 2160/4885THRB 1036/4885HCAR2 1252/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 LMNA 2160/4885THRB 1036/4885HCAR2 1252/4885
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 LMNA 2160/4885THRB 1036/4885HCAR2 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.