SCHEMBL4853499

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9909152	0.88	HTT (0.46)	KDM4EALDH1A1MAPK1DDR2LMNA
	SCHEMBL12367211	0.82	HTR1A (0.41)	KDM4EALDH1A1SLC22A12SMN1; SMN2SRC
	SCHEMBL591544	0.80	IDO1 (0.45)	IDO1AXLSLC22A12
	SCHEMBL26317945	0.80	SLC2A1 (0.51)	SLC2A1KDM4EMEN1KMT2AALDH1A1
	SCHEMBL2594936	0.80	GAK (0.47)	SLC22A12SMN1; SMN2
	SCHEMBL632944	0.80	LMNA (0.52)	KDM4EMEN1KMT2AMAPK1NPSR1
	SCHEMBL26632797	0.79	NR4A2 (0.45)	ALDH1A1MAPK1LMNAAXLSLC22A12
	SCHEMBL22492353	0.79	GAK (0.44)	IDO1AXLSLC22A12ESR2
	SCHEMBL3851998	0.79	SLC22A12 (0.56)	SLC22A12ESR2
	SCHEMBL14999154	0.78	SRC (0.39)	AXLSLC22A12SMN1; SMN2SRCTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.