Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.33 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871120 | 0.78 | TSHR (0.34) | TSHRKMT2AALDH1A1 | |
| SCHEMBL9581907 | 0.72 | KMT2A (0.46) | CYP2D6TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL9582187 | 0.70 | ALDH1A1 (0.43) | TSHRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1948855 | 0.69 | BCHE (0.44) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10835083 | 0.68 | NOTUM (0.59) | TSHRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL31565005 | 0.68 | NOTUM (0.59) | TSHRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL29182109 | 0.66 | KMT2A (0.53) | KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL5373174 | 0.65 | KDM4E (0.34) | — | |
| SCHEMBL32689427 | 0.64 | POLB (0.55) | KRASKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL811819 | 0.64 | POLB (0.55) | KRASKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144263-A1 | POTENT INDOLE-3-CARBINOL-DERIVED ANTITUMOR AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-11-27 | — | — | WO | disclosed |