SCHEMBL4853769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5016701	0.89	TP53 (0.41)	PDE4BPDE4APDE4CPDE4DTP53
	SCHEMBL18092188	0.88	MAPT (0.38)	ALDH1A1LMNA
	SCHEMBL4848394	0.86	USP2 (0.40)	PDE4BPDE4APDE4CPDE4DTP53
	SCHEMBL4253371	0.83	BACE1 (0.45)	GPR119LMNABACE1
	SCHEMBL14064668	0.83	ALDH1A1 (0.47)	TP53MEN1KMT2AGPR119ALDH1A1
	SCHEMBL4852633	0.82	RET (0.42)	PDE4BPDE4APDE4CPDE4DTP53
	SCHEMBL4251027	0.79	GPR119 (0.46)	TP53MEN1KMT2AGPR119LMNA
	SCHEMBL4848366	0.77	GPR119 (0.43)	PDE4BPDE4APDE4CPDE4DTP53
	SCHEMBL14064718	0.76	GPR119 (0.47)	MEN1KMT2AGPR119ALDH1A1LMNA
	SCHEMBL14064742	0.76	USP30 (0.40)	PDE4BPDE4APDE4CPDE4DGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.