Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022068 | 0.85 | AKR1C3 (0.40) | MAPTSMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL27671019 | 0.81 | RBP4 (0.44) | MAPTLMNAALDH1A1POLBHTT | |
| SCHEMBL5016701 | 0.77 | TP53 (0.41) | MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL27671027 | 0.76 | HTR1A (0.42) | MAPTSMN1; SMN2LMNAALDH1A1NPSR1 | |
| SCHEMBL18092180 | 0.72 | IDH1 (0.37) | FFAR4 | |
| SCHEMBL18092178 | 0.72 | IDH1 (0.37) | FFAR4 | |
| SCHEMBL4253371 | 0.71 | BACE1 (0.45) | MAPTLMNA | |
| SCHEMBL14064668 | 0.70 | ALDH1A1 (0.47) | MAPTSMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL4852633 | 0.69 | RET (0.42) | MAPTLMNAALDH1A1 | |
| SCHEMBL18092194 | 0.68 | RBP4 (0.44) | MAPTSMN1; SMN2RXFP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698620-B1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | EISAI R&D MAN CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |