Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.53 |
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684939 | 0.91 | TNFRSF1A (0.54) | MCHR1BCHETNFRSF1A | |
| SCHEMBL4847749 | 0.90 | ACHE (0.42) | MCHR1BCHEACHETNFRSF1AKDR | |
| SCHEMBL4848121 | 0.87 | BCHE (0.55) | MCHR1BCHEACHETNFRSF1ASLC6A9 | |
| SCHEMBL4849165 | 0.85 | BCHE (0.58) | MCHR1BCHEACHETNFRSF1A | |
| SCHEMBL4856388 | 0.84 | BCHE (0.49) | MCHR1BCHEACHESLC6A9 | |
| SCHEMBL4853797 | 0.84 | BCHE (0.49) | MCHR1BCHEACHESLC6A9 | |
| SCHEMBL4852888 | 0.81 | HCRTR2 (0.42) | MCHR1BCHEACHETNFRSF1AKDR | |
| SCHEMBL4853736 | 0.81 | BCHE (0.52) | MCHR1BCHEACHETNFRSF1ASLC6A9 | |
| SCHEMBL14280889 | 0.80 | BCHE (0.53) | MCHR1BCHEACHETNFRSF1ASLC6A9 | |
| SCHEMBL4853884 | 0.80 | BCHE (0.53) | MCHR1BCHEACHETNFRSF1ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | claimed |
| US-7423181-B2 | in particular against bacterial and parasitic infections, fungi, and helminths; improved metabolic and physiochemical properties, bioavailability, solubility; 3-[4-(2-Dimethylamino-ethoxy)-2'-trifluoromethyl-biphenyl-3-yl]-1-(2-dimethylaminomethyl-phenyl)-propenone | LICA PHARMACEUTICALS A/S (DK) | 2008-09-09 | — | — | US | disclosed |
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | disclosed |