Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849165 | 0.90 | BCHE (0.58) | BCHEACHEMCHR1MAOBALDH1A1 | |
| SCHEMBL4852218 | 0.88 | CAPN1 (0.50) | BCHEACHECAPN1MAOBCTSL | |
| SCHEMBL4853801 | 0.87 | MCHR1 (0.53) | BCHEACHEMCHR1SLC6A9TNFRSF1A | |
| SCHEMBL4853736 | 0.85 | BCHE (0.52) | BCHEACHEMCHR1SLC6A9KDM4E | |
| SCHEMBL14280889 | 0.84 | BCHE (0.53) | BCHEACHEMCHR1SLC6A9KDM4E | |
| SCHEMBL4853884 | 0.84 | BCHE (0.53) | BCHEACHEMCHR1SLC6A9KDM4E | |
| SCHEMBL4848110 | 0.82 | BCHE (0.51) | BCHEACHECAPN1MCHR1MAOB | |
| SCHEMBL4853434 | 0.82 | BCHE (0.51) | BCHEACHECAPN1MCHR1MAOB | |
| SCHEMBL4849762 | 0.82 | KDM4E (0.52) | BCHEACHECAPN1MAOBCTSL | |
| SCHEMBL14280884 | 0.80 | BCHE (0.46) | BCHEACHECAPN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | claimed |
| US-7423181-B2 | in particular against bacterial and parasitic infections, fungi, and helminths; improved metabolic and physiochemical properties, bioavailability, solubility; 3-[4-(2-Dimethylamino-ethoxy)-2'-trifluoromethyl-biphenyl-3-yl]-1-(2-dimethylaminomethyl-phenyl)-propenone | LICA PHARMACEUTICALS A/S (DK) | 2008-09-09 | — | — | US | disclosed |
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | disclosed |