Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.52 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852218 | 0.91 | CAPN1 (0.50) | BCHEACHETNFRSF1AMAPTRAB9A | |
| SCHEMBL4849986 | 0.91 | BCHE (0.46) | BCHEACHETNFRSF1A | |
| SCHEMBL14280884 | 0.91 | BCHE (0.46) | BCHEACHETNFRSF1A | |
| SCHEMBL4853514 | 0.90 | NR1H4 (0.47) | BCHEACHE | |
| SCHEMBL4856242 | 0.90 | BCHE (0.45) | BCHEACHETNFRSF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL4849921 | 0.90 | BCHE (0.45) | BCHEACHETNFRSF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL4856637 | 0.89 | LMNA (0.45) | BCHEACHETNFRSF1AALDH1A1KDM4E | |
| SCHEMBL4853345 | 0.89 | RELA (0.48) | BCHEACHETNFRSF1A | |
| SCHEMBL6386830 | 0.89 | ABCG2 (0.52) | BCHEACHETNFRSF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL4849810 | 0.88 | ABCB1 (0.43) | BCHEACHESLC6A9ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | claimed |
| US-7423181-B2 | in particular against bacterial and parasitic infections, fungi, and helminths; improved metabolic and physiochemical properties, bioavailability, solubility; 3-[4-(2-Dimethylamino-ethoxy)-2'-trifluoromethyl-biphenyl-3-yl]-1-(2-dimethylaminomethyl-phenyl)-propenone | LICA PHARMACEUTICALS A/S (DK) | 2008-09-09 | — | — | US | disclosed |
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | disclosed |