SCHEMBL4853803

SCHEMBL4853803

CCCCOCCC(N)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.56
NOS3 P29474 1/20 0.56
NOS2 P35228 1/20 0.56
SLC1A2 P43004 5/20 0.55
SLC1A1 P43005 5/20 0.55
SLC1A3 P43003 4/20 0.55
GRIK1 P39086 6/20 0.53
GRIK2 Q13002 5/20 0.53
DDAH1 O94760 3/20 0.46
GSR P00390 2/20 0.44
P2RY10 O00398 1/20 0.44
TSHR P16473 1/20 0.43
NOD1 Q9Y239 2/20 0.42
SLC7A5 Q01650 1/20 0.42
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
CYP1A2 P05177 1/20 0.42
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4853808 1.00 NOS1 (0.56) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL516471 0.93 GRIK1 (0.57) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL8063263 0.91 GSR (0.52) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL21952409 0.88 NOS1 (0.59) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL20751441 0.88 NOS1 (0.59) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL21335891 0.85 GSR (0.48) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL25660613 0.83 NOS3 (0.54) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL2757451 0.82 NOS3 (0.54) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL5607813 0.82 NOS3 (0.54) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL25660616 0.82 NOS3 (0.57) NOS1NOS3NOS2SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US claimed
WO-2004021981-A2 METHODS FOR THE PREPARATION OF β-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-03-18 WO claimed
US-20030113882-A1 Methods for the preparation of beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-06-19 US claimed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO disclosed
WO-2025070731-A1 PEPTIDEPEPTIDE ペプチドリーム株式会社 2025-04-03 WO disclosed
WO-2025070720-A1 PEPTIDE ペプチドリーム株式会社 2025-04-03 WO disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 WO disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 WO disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
CN-102471489-B Supermolecule polymer and the compositions comprising described polymer 罗地亚经营管理公司 2016-08-03 CN disclosed
US-9012567-B2 Supramolecular polymers and compositions containing said polymers RHODIA OPERATIONS (FR) 2015-04-21 US disclosed
US-20120289652-A1 SUPRAMOLECULAR POLYMERS AND COMPOSITIONS CONTAINING SAID POLYMERS RHODIA OPERATIONS (FR) 2012-11-15 US disclosed
CN-102471489-A Supramolecular polymers and compositions comprising said polymers RHODIA OPERATIONS 2012-05-23 CN disclosed
US-7452701-B2 Methods for the preparation of β-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-11-18 US disclosed
WO-2004021981-A2 METHODS FOR THE PREPARATION OF β-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-03-18 WO disclosed
US-20030113882-A1 Methods for the preparation of beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP NOS1 1488/4885NOS3 1214/4885NOS2 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.