SCHEMBL48545

SCHEMBL48545

CC(=O)Cc1ccc(F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.53
POLB P06746 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
APEX1 P27695 1/20 0.53
CTBP2 P56545 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 3/20 0.50
HTT P42858 3/20 0.50
KDM4E B2RXH2 2/20 0.50
KMT2A Q03164 1/20 0.50
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 1/20 0.47
RAB9A P51151 1/20 0.47
EGFR P00533 1/20 0.47
ERBB2 P04626 1/20 0.47
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9266213 0.94 TDP1 (0.49) GAAPOLBTDP1APEX1CTBP2
SCHEMBL9269526 0.88 POLB (0.56) GAAPOLBTDP1APEX1SMN1; SMN2
SCHEMBL8403545 0.87 POLB (0.61) GAAPOLBLMNAHTTKMT2A
SCHEMBL11253749 0.84 GAA (0.57) GAASMN1; SMN2LMNAKDM4EKMT2A
SCHEMBL2208662 0.83 GAA (0.52) GAAPOLBTDP1APEX1CTBP2
SCHEMBL28138970 0.81 KMT2A (0.47) GAACTBP2SMN1; SMN2LMNAKDM4E
SCHEMBL1515223 0.80 CTBP2 (0.56) GAAPOLBTDP1APEX1CTBP2
SCHEMBL1620786 0.80 TDP1 (0.47) GAAPOLBTDP1APEX1CTBP2
SCHEMBL10775630 0.80 POLB (0.55) POLBTDP1KDM4EKMT2AHSD17B10
SCHEMBL526194 0.80 GAA (0.57) GAAPOLBTDP1APEX1CTBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 747 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684105-A N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method 贵州医科大学 2025-03-25 CN claimed
CN-119552838-A Amine dehydrogenase catalytic system, application thereof and eutectic solvent and preparation thereof 河北工业大学 2025-03-04 CN claimed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN claimed
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP claimed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
CN-113663463-B Odor inhibitor 日东生物科技(浙江)有限公司 2022-08-02 CN claimed
CN-114574455-A Method for forming supramolecular hydrogel for biocatalysis by utilizing enzyme self-assembly 清华大学 2022-06-03 CN claimed
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
CN-112374974-A Method for synthesizing isomagnoflorine 郑州大学 2021-02-19 CN claimed
US-20160340544-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2016-11-24 US claimed
EP-3088487-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2016-11-02 EP claimed
CN-105849222-A Surface treating agent comprising perfluoro (poly) ether group-containing silane compound 大金工业株式会社 2016-08-10 CN claimed
CN-104710256-A Cheap and efficient synthesis method of alpha-hydroxyketone compound UNIV BEIJING 2015-06-17 CN claimed
CN-101891569-B Preparation method of alpha-aromatic ketone compound UNIV WUHAN 2013-07-24 CN claimed
CN-102311457-A Preparation method of rosuvastatin SUZHOU LAKESTAR PHARMATECH CO LTD 2012-01-11 CN claimed
EP-1670314-A4 METHODS AND COMPOSITIONS COMPRISING DIAMINES AS NEW ANTI-TUBERCULAR THERAPEUTICS SEQUELLA INC (US) 2009-02-25 EP claimed
EP-1670314-A2 METHODS AND COMPOSITIONS COMPRISING DIAMINES AS NEW ANTI-TUBERCULAR THERAPEUTICS Sequella, Inc. (US) 2006-06-21 EP claimed
US-20050113574-A1 Methods and compositions comprising diamines as new anti-tubercular therapeutics SEQUELLA, INC. 2005-05-26 US claimed
WO-2005034857-A2 METHODS AND COMPOSITIONS COMPRISING DIAMINES AS NEW ANTI-TUBERCULAR THERAPEUTICS SEQUELLA, INC. (US) 2005-04-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113574-A1 Methods and compositions comprising diamines as new anti-tubercular therapeutics C5, DDC, SAT1 GAA 466/4885POLB 101/4885TDP1 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.