Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252721 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1TRPV1POLB | |
| SCHEMBL14223876 | 0.81 | NPC1 (0.56) | RAB9ASMN1; SMN2NPC1NPSR1ALDH1A1 | |
| SCHEMBL455628 | 0.81 | NAMPT (0.56) | RAB9ASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL14223443 | 0.80 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1NPSR1ALDH1A1 | |
| SCHEMBL4856199 | 0.80 | CYP11B1 (0.51) | RAB9ASMN1; SMN2NPC1POLBTP53 | |
| SCHEMBL4854662 | 0.79 | KMT2A (0.52) | RAB9ASMN1; SMN2NPC1POLBNPSR1 | |
| SCHEMBL4863530 | 0.79 | KDM4E (0.59) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL5594818 | 0.77 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4855896 | 0.77 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL28614091 | 0.74 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1TRPV1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365069-B2 | Pyrimidone derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20040259891-A1 | Novel pyrimidon derivatives | ORCHID CHEMICAL & PHARMACEUTICALS LIMITED (IN) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259891-A1 | Novel pyrimidon derivatives | TYMS, TPMT, TYMP | RAB9A 2079/4885SMN1; SMN2 2461/4885NPC1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.