Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 11/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 11/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5015868 | 0.99 | CARM1 (0.44) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| SCHEMBL4251023 | 0.86 | DRD2 (0.50) | HTR1AADRA1BSIGMAR1 | |
| SCHEMBL4858220 | 0.85 | HTR1A (0.43) | HTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL4850972 | 0.85 | DRD2 (0.49) | HTR1AADRA1BSIGMAR1 | |
| SCHEMBL9853259 | 0.84 | CARM1 (0.55) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4859556 | 0.84 | HTR1A (0.42) | HTR1AADRA1B | |
| SCHEMBL4256037 | 0.84 | KDM4E (0.53) | HTR1AADRA1B | |
| SCHEMBL14072983 | 0.83 | CHRNA7 (0.44) | HTR1AADRA1BSIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL9739959 | 0.83 | CARM1 (0.54) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| SCHEMBL4857776 | 0.83 | DRD2 (0.48) | HTR1AADRA1BTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425554-B2 | 1,2-di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| US-20050261291-A1 | 1,2-Di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261291-A1 | 1,2-Di(cyclic)substituted benzene compounds | CCR10, HRH3, HRH2 | CARM1 526/4885PRMT6 1661/4885HTR1A 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.