Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 14/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 14/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9739959 | 0.99 | CARM1 (0.54) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| SCHEMBL8297825 | 0.92 | HTR1A (0.50) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9134644 | 0.91 | HTR1A (0.49) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| SCHEMBL4855424 | 0.84 | CARM1 (0.45) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL5015868 | 0.83 | CARM1 (0.44) | CARM1PRMT6HTR1AADRA1BSIGMAR1 | |
| SCHEMBL27433853 | 0.79 | HTR1A (0.48) | HTR1AADRA1BSIGMAR1 | |
| SCHEMBL8828503 | 0.78 | CYP2D6 (0.56) | HTR1AADRA1BSIGMAR1 | |
| SCHEMBL23064518 | 0.78 | ADRA2C (0.55) | HTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL4859668 | 0.77 | DRD2 (0.54) | HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4856751 | 0.76 | DRD2 (0.47) | HTR1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435749-A1 | Derivatives of 2-aminopyrimidine-4-carboxamide, their preparation and therapeutic use | SYNTHELABO (FR) | 1991-07-03 | — | — | EP | disclosed |