Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606121 | 0.87 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL4393654 | 0.87 | HDAC6 (0.40) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL29873697 | 0.85 | CA12 (0.45) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL12519845 | 0.82 | HDAC6 (0.38) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL13564256 | 0.81 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL4925900 | 0.81 | ALDH1A1 (0.52) | TDP1TSHRHPGDALDH1A1 | |
| SCHEMBL9986542 | 0.79 | CYP1A2 (0.36) | HDAC6HDAC1HDAC2CA12CA1 | |
| Ammonia Solution, Strong SCHEMBL21642596 | 0.79 | ALDH1A1 (0.50) | TDP1TSHRHPGDALDH1A1 | |
| SCHEMBL14982599 | 0.79 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL1538325 | 0.79 | NAAA (0.50) | CA12CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378548-B2 | Tertiary amine compounds having an ester structure and processes for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | claimed |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | SHIN-ETSU CHEMICAL CO., LTD. | 2006-09-28 | — | — | US | claimed |
| EP-2692728-B1 | NOVEL FURANONE DERIVATIVE | CARNA BIOSCIENCES INC (JP) | 2018-07-04 | — | — | EP | disclosed |
| EP-2692728-A1 | NOVEL FURANONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2014-02-05 | — | — | EP | disclosed |
| US-7378548-B2 | Tertiary amine compounds having an ester structure and processes for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| EP-1253138-B1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHINETSU CHEMICAL CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | SHIN-ETSU CHEMICAL CO., LTD. | 2006-09-28 | — | — | US | disclosed |
| US-7084303-B2 | Tertiary amine compounds having an ester structure and processes for preparing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20020193622-A1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHIN-ETSU CHEMICAL CO., LTD. | 2002-12-19 | — | — | US | disclosed |
| EP-1253138-A2 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-10-30 | — | — | EP | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193622-A1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | PHOSPHO1, NAAA, DDAH1 | HDAC6 4252/4885HDAC1 2950/4885HDAC2 3632/4885 |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | HRH3, HRH4, HRH2 | HDAC6 3643/4885HDAC1 2476/4885HDAC2 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.