Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 4/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681252 | 1.00 | LMNA (0.52) | LMNAPRKDCPIK3CAMTORATM | |
| SCHEMBL24680783 | 1.00 | LMNA (0.52) | LMNAPRKDCPIK3CAMTORATM | |
| SCHEMBL21256942 | 0.84 | ADRB1 (0.43) | PRKDCPIK3CAMTORATMSYK | |
| SCHEMBL21256947 | 0.84 | ADRB1 (0.43) | PRKDCPIK3CAMTORATMSYK | |
| SCHEMBL14167561 | 0.82 | MAPT (0.46) | LMNAPRKDCPIK3CAMTORSYK | |
| SCHEMBL25287660 | 0.82 | PRKDC (0.39) | PRKDCPIK3CAMTORATMPIK3C3 | |
| SCHEMBL19863415 | 0.82 | AKR1C3 (0.41) | PRKDCPIK3CAMTORATMPIK3C3 | |
| SCHEMBL19863416 | 0.82 | AKR1C3 (0.41) | PRKDCPIK3CAMTORATMPIK3C3 | |
| SCHEMBL14167611 | 0.82 | AKR1C3 (0.41) | PRKDCPIK3CAMTORATMPIK3C3 | |
| SCHEMBL28317142 | 0.82 | CHKA (0.46) | PRKDCPIK3CAMTORATRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127728-A1 | MODIFIED GRAPHENE, METHOD OF PRODUCING MODIFIED GRAPHENE, MODIFIED GRAPHENE-RESIN COMPOSITE, MODIFIED GRAPHENE SHEET, AND MODIFIED GRAPHENE DISPERSION | CANON KK (JP) | 2023-04-27 | — | — | US | disclosed |
| US-11518889-B2 | Modified graphene, method of producing modified graphene, modified graphene-resin composite, modified graphene sheet, and modified graphene dispersion | CANON KABUSHIKI KAISHA (JP) | 2022-12-06 | — | — | US | disclosed |
| WO-2022226667-A1 | SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-11-03 | — | — | WO | disclosed |
| CN-113072460-B | Morpholine derivative oxidation ring-opening method and product thereof | 西南大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113072460-A | Morpholine derivative oxidation ring-opening method and product thereof | 西南大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-111755748-A | Electrolyte additive, electrolyte and lithium ion secondary battery comprising same | 株式会社村田制作所 | 2020-10-09 | — | — | CN | disclosed |
| US-20200313240-A1 | ELECTROLYTE ADDITIVE, ELECTROLYTE AND LITHIUM ION SECONDARY BATTERY CONTAINING THE SAME | MURATA MANUFACTURING CO., LTD. (JP) | 2020-10-01 | — | — | US | disclosed |
| US-20200270463-A1 | MODIFIED GRAPHENE, METHOD OF PRODUCING MODIFIED GRAPHENE, MODIFIED GRAPHENE-RESIN COMPOSITE, MODIFIED GRAPHENE SHEET, AND MODIFIED GRAPHENE DISPERSION | CANON KABUSHIKI KAISHA (JP) | 2020-08-27 | — | — | US | disclosed |
| EP-2917194-B1 | NOVEL BENZYL SULFONAMIDE COMPOUNDS USEFUL AS MOGAT-2 INHIBITORS | LILLY CO ELI (US) | 2017-09-27 | — | — | EP | disclosed |
| US-9416138-B2 | Benzyl sulfonamide compounds useful as MoGAT-2 inhibitors | ELI LILLY AND COMPANY (US) | 2016-08-16 | — | — | US | disclosed |
| US-7371771-B2 | Alkenyl-substituted spirocyclic sulfamides as inhibitors of gamma-secretase | MERCK SHARP & DOHME LTD. (GB) | 2008-05-13 | — | — | US | disclosed |
| CN-1279034-C | DNA-PK inhibitors | CANCER REC TECH LTD (GB) | 2006-10-11 | — | — | CN | disclosed |
| US-20050182111-A1 | Alkenyl-substituted spirocyclic sulfamides as inhibitors of gamma-secretase | MERCK SHARP & DOHME LTD. (GB) | 2005-08-18 | — | — | US | disclosed |
| CN-1543457-A | DNA-PK inhibitors | ��֢�о���������˾ | 2004-11-03 | — | — | CN | disclosed |
| EP-1417196-A1 | DNA-PK INHIBITORS | Cancer Research Technology Limited (GB) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003093251-A1 | ALKENYL-SUBSTITUTED SPIROCYCLIC SULFAMIDES AS INHIBITORS OF GAMMA-SECRETASE | MERCK SHARP & DOHME LIMITED (GB) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| CN-1092412-A | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-09-21 | — | — | CN | disclosed |
| US-4384968-A | TREATING GAS STREAM WITH MORPHOLINE OR SERIVATIVE | BETZ LABORATORIES, INC. (US) | 1983-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270463-A1 | MODIFIED GRAPHENE, METHOD OF PRODUCING MODIFIED GRAPHENE, MODIFIED GRAPHENE-RESIN COMPOSITE, MODIFIED GRAPHENE SHEET, AND MODIFIED GRAPHENE DISPERSION | GRIA1, GRIN1, NR3C1 | LMNA 1145/4885PRKDC 4875/4885PIK3CA 4026/4885 |
| US-20230127728-A1 | MODIFIED GRAPHENE, METHOD OF PRODUCING MODIFIED GRAPHENE, MODIFIED GRAPHENE-RESIN COMPOSITE, MODIFIED GRAPHENE SHEET, AND MODIFIED GRAPHENE DISPERSION | GRIA1, GRIN1, NR3C1 | LMNA 1129/4885PRKDC 4875/4885PIK3CA 4018/4885 |
| US-20050182111-A1 | Alkenyl-substituted spirocyclic sulfamides as inhibitors of gamma-secretase | BACE1, BACE2, GSAP | LMNA 2359/4885PRKDC 4773/4885PIK3CA 2556/4885 |
| US-11518889-B2 | Modified graphene, method of producing modified graphene, modified graphene-resin composite, modified graphene sheet, and modified graphene dispersion | GRIA1, GRIN1, NR3C1 | LMNA 1145/4885PRKDC 4875/4885PIK3CA 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.