Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27332844 | 0.81 | KMT2A (0.49) | MAPTALDH1A1NPSR1HTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27337866 | 0.81 | PRMT5 (0.36) | CYP2C9TSHRMAPTALDH1A1LMNA | |
| SCHEMBL30535515 | 0.79 | MAOA (0.46) | CYP2C9MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25351991 | 0.79 | MAOA (0.46) | CYP2C9MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27313258 | 0.78 | MAPKAPK2 (0.48) | CYP2C9MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18865780 | 0.77 | LOXL2 (0.44) | GRM5 | |
| SCHEMBL28287783 | 0.77 | NOTUM (0.47) | MAPTALDH1A1LMNANPSR1L3MBTL1 | |
| SCHEMBL7674620 | 0.74 | GRM5 (0.56) | ALDH1A1SMN1; SMN2GRM5NPC1RAB9A | |
| SCHEMBL27330187 | 0.74 | HTT (0.60) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL28287787 | 0.73 | HPN (0.49) | TSHRMAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101965350-A | Novel pyrazolo [3,4-d ] pyrimidine derivatives as anticancer agents | NATCO PHARMA LTD | 2011-02-02 | — | — | CN | claimed |
| CN-101070305-B | Process for producing N-phenylpyrazolecarbonitrile | LIANYUNGANG SINOCHEM CHEMICALS CO., LTD. (CN) | 2012-02-22 | — | — | CN | disclosed |
| CN-101965350-A | Novel pyrazolo [3,4-d ] pyrimidine derivatives as anticancer agents | NATCO PHARMA LTD | 2011-02-02 | — | — | CN | disclosed |
| US-7371768-B2 | Pyrazol derivatives, pest control agent comprising the same as active ingredient, and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| CN-101070305-A | Process for producing N-phenylpyrazolecarbonitrile | LIANYUNGANG ZHONGHUA CHEMICAL (CN) | 2007-11-14 | — | — | CN | disclosed |
| EP-1197492-B1 | PYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME, AND PESTICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | NIHON NOHYAKU CO LTD (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1310497-B1 | PYRAZOLE DERIVATIVE, PEST CONTROL AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT AND PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-6849633-B2 | Pyrazole derivative, production process thereof, and pest control agent containing the same as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 2005-02-01 | — | — | US | disclosed |
| US-20040053969-A1 | Pyrazol derivatives, pest control agent comprising the same as active ingredient, and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| JP-2004018487-A | NOXIOUS ORGANISM CONTROLLING AGENT COMPOSITION AND NOXIOUS ORGANISM CONTROLLING METHOD | SUMITOMO CHEM CO LTD | 2004-01-22 | — | — | JP | disclosed |
| EP-1197492-A1 | PYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME, AND PESTICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 2002-02-07 | — | — | US | disclosed |
| US-6162820-A | Method for removing parasites and in particular ectoparasites of vertebrates, in particular of mammals, and compositions for the implementation of this method | MERIAL (FR) | 2000-12-19 | — | — | US | disclosed |
| EP-0948487-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028279-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998002042-A1 | METHODS FOR ELIMINATING PARASITES AND IN PARTICULAR ECTOPARASITES OF VERTEBRATES, PARTICULARLY OF MAMMALS AND COMPOSITIONS FOR IMPLEMENTING THESE METHODS | MERIAL (FR) | 1998-01-22 | — | — | WO | disclosed |
| US-5707934-A | Plant growth regulation using 3-cyano-1-phenylpyrazoles such as fipronil | RHONE-POULENC INC. (US) | 1998-01-13 | — | — | US | disclosed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | disclosed |
| US-5585329-A | Plant growth promotion using 3-cyano-1-phenylpyrazoles such as fipronil | RHONE-POULENC INC. (US) | 1996-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053969-A1 | Pyrazol derivatives, pest control agent comprising the same as active ingredient, and process for producing the same | CTRL, AADAC, CBR3 | CYP2C9 99/4885TSHR 2185/4885MAPT 4791/4885 |
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | DDT, NAT1, CYP2E1 | CYP2C9 35/4885TSHR 162/4885MAPT 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.