Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.39 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100260 | 0.81 | GRM5 (0.45) | GRM5MTORCYP1A2GRIA1 | |
| SCHEMBL30794613 | 0.75 | GRM5 (0.59) | GRM5MTORPLAURPKMGRIA1 | |
| SCHEMBL4855602 | 0.74 | CYP2C9 (0.47) | GRM5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL12075251 | 0.73 | GRM5 (0.47) | GRM5PLAURKDM4EPKMMEN1 | |
| SCHEMBL26107606 | 0.73 | KCNJ1 (0.36) | GRM5KDM4ENPC1ALDH1A1 | |
| SCHEMBL1907360 | 0.73 | MAPT (0.63) | GRM5MTORALKBH2EGLN1RPTOR | |
| SCHEMBL2160327 | 0.73 | MPO (0.46) | GRM5MTORALKBH2EGLN1RPTOR | |
| SCHEMBL2643353 | 0.73 | GRM5 (0.46) | GRM5MTORALKBH2EGLN1RPTOR | |
| SCHEMBL38651177 | 0.73 | MAPT (0.63) | GRM5MTORALKBH2EGLN1RPTOR | |
| SCHEMBL29563483 | 0.73 | MPO (0.46) | GRM5MTORALKBH2EGLN1RPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016084866-A1 | NOVEL DIAZABICYCLO DERIVATIVE | 持田製薬株式会社 | 2016-06-02 | — | — | WO | disclosed |
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 2002-02-07 | — | — | US | disclosed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | DDT, NAT1, CYP2E1 | GRM5 947/4885MTOR 3952/4885ALKBH2 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.