Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443562 | 0.92 | CA2 (0.43) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL8891862 | 0.84 | SLC6A5 (0.43) | FFAR1MAPTPPARD | |
| Propylamine SCHEMBL7723165 | 0.83 | CA2 (0.46) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL29144960 | 0.80 | CA2 (0.48) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL27494955 | 0.78 | CA2 (0.48) | CA2MAPK1GRIK1GRIK2CA1 | |
| SCHEMBL8397773 | 0.75 | CA2 (0.44) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL8398739 | 0.75 | CA2 (0.44) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL8396450 | 0.75 | CA2 (0.44) | CA2GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL8394136 | 0.75 | CA2 (0.44) | CA2GRIK1GRIK2GPR84SLC1A2 | |
| SCHEMBL8398002 | 0.75 | CA2 (0.44) | CA2GRIK1GRIK2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361712-B2 | Water absorbing agent, process for its production, and absorbers and absorbent articles made by using the agent | SAN-DIA POLYMERS, LTD. (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20050080194-A1 | Water absorbing agent, process for its production, and absorbers and absorbent articles made by using the agent | SAN-DIA POLYMERS, LTD. (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1457541-A1 | WATER ABSORBING AGENT, PROCESS FOR ITS PRODUCTION, AND ABSORBERS AND ABSORBENT ARTICLES MADE BY USING THE AGENT | San-Dia Polymers, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |